CGT Wiki
Gene and cell therapy terminology, workflows, evidence, and technical reference.
AAV Knowledge Base
A structured AAV knowledge base covering fundamentals, serotype selection, administration, dosing, expression assessment, and tissue-specific delivery.
AAV structure and recombinant vector
AAV, AAV Knowledge Base
ssAAV, scAAV and packaging capacity
AAV, AAV Knowledge Base
Titer, dose and particle quality
AAV, AAV Knowledge Base
AAV advantages, limitations and immune factors
AAV, AAV Knowledge Base
Selecting Vector Functions by Research Objective
AAV, AAV Knowledge Base
Six Variables for Serotype Selection
A practical framework for selecting natural and engineered AAV serotypes based on target tissue, cell type, species, strain, administration route, and translational evidence.
Promoter and expression control selection
AAV, AAV Knowledge Base
Administration Routes, Dosing, and Expression Assessment
Route-specific guidance for AAV administration, dose selection, cross-species scaling, safety considerations, and expression-assessment time points.
General Principles for Tissue Application
AAV, AAV Knowledge Base
Tissue-Specific Targeted Delivery Strategies
Evidence-based AAV delivery strategies for the retina, liver, heart, skeletal muscle, bone, lung, kidney, pancreas, adipose tissue, and skin.
Special Topics in Neuroscience
AAV, AAV Knowledge Base
Tissue-Application Evidence Grading
AAV, AAV Knowledge Base
Natural serotypes, engineered capsids and screening
AAV, AAV Knowledge Base
Translational Risks in Capsid Development
AAV, AAV Knowledge Base