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Chemogenetics

rAAV-nEF1α-Con Fon-hM4D(Gi)-EYFP

hM4Di is an engineered receptor (DREADD) derived from the human muscarinic acetylcholine receptor M4 (hM4D) that responds only to CNO and is no longer activated by acetylcholine. In certain neurons, CNO binding to hM4D activates Gi protein-coupled inward potassium channels (GIRK), leading to cell membrane hyperpolarization and inhibition of neuronal action potential firing.

Product No.CS-3083
Serotype

AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro

Receptor

hM4Di(Gi)

Promoter

Broad-spectrum Promoter

Storage

Store at -80°C

Volume
1E+12GC
1E+12GC>1E+14GC
Titer
≥1E+13GC/mL
≥1E+13GC/mL≥5E+12GC/mL
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Delivery Information

Usually Ships in 7 Business Days;

Product Details

Fluorescent Tag

EYFP

Fluorescent Protein Details

EYFP: Yellow fluorescent protein, excitation wavelength 513nm, emission wavelength 527nm.

Expression and Regulation Mode

Boolean Algebra