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Chemogenetics
rAAV-hSyn-hM4D(Gi)-P2A-mCherry
hM4Di is an engineered receptor (DREADD) derived from the human muscarinic acetylcholine receptor M4 (hM4D) that responds only to CNO and is no longer activated by acetylcholine. In certain neurons, CNO binding to hM4D activates Gi protein-coupled inward potassium channels (GIRK), leading to cell membrane hyperpolarization and inhibition of neuronal action potential firing.
Product No.CS-2810
Serotype
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
Receptor
hM4Di(Gi)
Promoter
Neuron-specific Promoter
Storage
Store at -80°C
Volume
Titer
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Actions
Delivery Information
Usually Ships in 7 Business Days;
Product Details
Fluorescent Tag
mCherry
Fluorescent Protein Details
mCherry: red fluorescent protein, excitation wavelength 587nm, emission wavelength 610nm.

