Optogenetics
rAAV-hSyn-DIO-ReaChR-Citrine
This AAV expresses ReaChR-Citrine driven by a neuron CaMKIIα promoter. ReaChR(denoted red-activatable ChR) is a variant of ChR, is optimally excited with orange to red light (λ ∼590-630 nm) . Compared to existing red-shifted ChRs , it improved membrane trafficking, higher photocurrents and faster kinetics. Citrine is a basic (constitutively fluorescent) yellow fluorescent protein published in 2001, derived from Aequorea victoria, with a Excitation/Emission spectrum around 516nm/529nm. It has moderate acid sensitivity.
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
ReaChR
Neuron-specific Promoter
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Delivery Information
Usually Ships in 7 Business Days；
Product Details
Functional Gene Details
ReachR: red-activatable ChR, is an optogenetic tool modified by Tsien's laboratory based on vChR1 that can respond to red light with a wavelength of 590 to 630nm. In the range of 10 Hz and below, cortical neurons expressing ReachR can be directly activated by extracranial light administration. However, ReachR can also be excited by blue light.
Fluorescent Tag
Citrine
Fluorescent Protein Details
Citrine: yellow fluorescent protein, excitation wavelength 516nm, emission wavelength 529nm.
Expression and Regulation Mode
Cre-dependent
