Optogenetics
rAAV-hSyn-DIO-eArch3.0-EYFP
Compared with Arch, it has a wider dynamic range and off-target effects when applied to the presynaptic terminal.
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
eArch3.0
Neuron-specific Promoter
Store at -80°C
Delivery Information
Usually Ships in 7 Business Days；
Product Details
Functional Gene Details
eArch3.0, enhanced light-driven outward hydrogen ion pump, is an engineered variant of Arch (Archaerhodopsin-3). After light activation, hydrogen ions can be pumped from intracellular to extracellular, thereby inducing hyperpolarization of neurons and inhibiting electrical activity. The excitation wavelength is approximately 566 nm. Compared with the original Arch, eArch3.0 achieves higher expression efficiency by optimizing membrane positioning, resulting in stronger photocurrent at the same expression level.
Fluorescent Tag
EYFP
Fluorescent Protein Details
EYFP: Yellow fluorescent protein, excitation wavelength 513nm, emission wavelength 527nm.
Expression and Regulation Mode
Cre-dependent
