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Optogenetics

AAV2/9-CaMKIIa-eArchT 3.0-P2A-EGFP-WPRE-hGHpA

Product No.CS-0438
Serotype

AAV2/9

Receptor

ArchT

Promoter

mCaMKIIa(1.3k)

Storage

Store at -80°C

Volume
1E+12GC
1E+12GC>1E+14GC
Titer
≥1E+13GC/mL
≥1E+13GC/mL≥5E+12GC/mL
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Delivery Information

Usually Ships in 7 Business Days;

Product Details

Promoter Details

CaMKIIa, pyramidal neuron/excitatory neuron promoter, 1293bp.

Functional Gene Details

ArchT: Light-driven outward hydrogen ion pump, belonging to Archaerhodopsin. Compared with Arch, although the maximum current it can form is similar to Arch, ArchT is more than three times more sensitive to light and performs well under 1–10 mW/mm2 illumination. Therefore, under the same conditions, the area that can be suppressed is about twice that of Arch. Its maximum activation wavelength is around 570nm, and it can also be activated with light around 532nm. In some neurons, concentrated firing of action potentials occurs after continuous light inhibition.

Fluorescent Tag

green fluorescent green

Virus Type

Adeno-associated virus vector Adeno-associated Virus

Expression and Regulation Mode

specific expression