Optogenetics
AAV2/5-mCaMKIIa-C1V1(t/t)-EYFP-WPRE-pA
AAV2/5, AAV2/9
C1V1 C1V1(E122T/E162T)
mCaMKIIa mCaMKIIa(1.3k)
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Delivery Information
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Product Details
Promoter Details
CaMKIIa, pyramidal neuron/excitatory neuron promoter, 1293bp.
m C aMKIIa promoter, cloned from the promoter region of mouse calmodulin-dependent protein kinase IIa, is 1.3kb in length and is specifically expressed in excitatory neuronal cells.
Functional Gene Details
C1V1: It is a new ion channel formed by the fusion of ChR1 and VChR1 fragments. This protein is very sensitive. C1V1 expressed in C. elegans can work under 0.2-0.5mW/mm2 light. The maximum absorption wavelength is 540-580nm. It can also be activated by 400nm laser. The common C1V1 carries two point mutations, E122T and E162T, to improve activity, so it is also called C1V1(t/t). The excitation light wavelength is 560nm.
Fluorescent Tag
yellow fluorescent yellow
Virus Type
Adeno-associated virus vector Adeno-associated Virus
Expression and Regulation Mode
specific expression
