HSV-helper
rAAV-UL26.5-DIO-cmgD
AAV selects the UL26.5 promoter of the HSV structural protein gene UL26.5 (UL26.5p) to drive the expression of the gD protein, enabling abundant expression only in cells infected with Hs06. Considering that the chimeric protein scHer2/gD in Hs06 contains parts of the gD sequence, we performed codon optimization on the gD sequence in AAV, referred to as cmgD.
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
cmgD
Broad-spectrum Promoter
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Delivery Information
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Product Details
Fluorescent Tag
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Fluorescent Protein Details
mCitrine: yellow fluorescent protein, excitation wavelength 516nm, emission wavelength 529nm. Tag protein: HA: The HA tag protein sequence is YPYDVPDYA, which is derived from the hemagglutinin surface epitope of influenza virus. It has 9 amino acids and has little impact on the spatial structure of the foreign target protein. It is easy to construct a tag protein fused to the N-terminus or C-terminus. Easy to detect with Anti-HA antibody detection and ELISA. IRES: internal ribosome entry site, the Chinese name is the internal ribosome entry sequence, which can be inserted downstream of the CDS region on the mRNA to mediate another CDS region that follows it, thus enabling the expression of two proteins on one mRNA.
Expression and Regulation Mode
Cre-dependent
