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Chemogenetics

rAAV-mIBA1-miniDi-P2A-mCherry-WPRE-4×miR9T

A recombinant AAV designed for microglia-specific chemogenetic inhibition. The mIba1 promoter enables selective expression in microglia. The inhibitory DREADD receptor miniDi suppresses cell activity upon activation by CNO or DCZ, depending on the experimental animal species. Four miR-9 target sites reduce off-target neuronal expression.

Product No.CS-3008
Serotype

AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro

Receptor

miniDi-P2A-mCherry

Promoter

mIba1

Storage

Store at -80°C

Volume
1E+12GC
1E+12GC>1E+14GC
Titer
≥1E+13GC/mL
≥1E+13GC/mL≥5E+12GC/mL
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Delivery Information

Usually Ships in 7 Business Days;

Product Details

Promoter Details

mIba1

Fluorescent Tag

mCherry

Fluorescent Protein Details

mCherry: red fluorescent protein, excitation wavelength 587nm, emission wavelength 610nm.

Application

Chemogenetics (microglia modulation)