Calcium Sensors
rAAV-hSyn-NES-SomaFRCaMPi
Compared to the widely used jRGECOla, FRCaMPi and soma-localized FRCaMPi (SomaFRCaMPi) exhibit up to 2-fold higher dynamic range and peak ΔF/F0 action potentials in cultured neurons and in vivo. In wide-field imaging of the mouse primary somatosensory and visual cortex with high labeling density (80-90%), SomaFRCaMPi shows up to a 40% improvement in signal-to-noise ratio (SNR) and reduces spurious correlations between neurons. Overall, SomaFRCaMPi significantly enhances the accuracy and scale of neuronal activity imaging at single-neuron resolution in densely labeled brain tissues, with 2 to 3 times improved automated neuronal segmentation efficiency, a 50% increase in the fraction of responsive cells, and up to a 2-fold increase in SNR compared to jRGECOla.
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro, AAV2/9
SomaFRCaMPi somaFRCaMPi
Neuron-specific Promoter hSyn
Store at -80°C
Delivery Information
Usually Ships in 7 Business Days；
Product Details
Promoter Details
hSyn, human synapsin promoter, mature neuron-specific promoter, 448bp.
Fluorescent Tag
mApple
red fluorescent red
Fluorescent Protein Details
dsRed, red fluorescent protein, excitation wavelength 557nm, emission wavelength 579nm.
Virus Type
Adeno-associated virus vector Adeno-associated Virus
Expression and Regulation Mode
specific expression
