Calcium Sensors
rAAV-hSyn-NEMOc
The novel fluorescent protein probe, NEMOs, offers stronger fluorescent signals and more precise quantitative measurement capabilities. It uses the brighter fluorescent protein mNeoGreen (mNG) to replace the widely used cpGFP. Compared to the best genetically encoded calcium indicators (GECIs) available so far, NEMO calcium indicators exhibit significantly higher cellular dynamic range (DR). The DR of NEMOs and NEMOb is at least 4.5 times greater than that of GCaMP6m or NCaMP7, while NEMOm and NEMOc outperform GCaMP6m or NCaMP7 by 9.5 to 25.7 times.
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
NEMOc
Neuron-specific Promoter
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Delivery Information
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Product Details
Fluorescent Tag
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Fluorescent Protein Details
mCitrine: yellow fluorescent protein, excitation wavelength 516nm, emission wavelength 529nm. Tag protein: HA: The HA tag protein sequence is YPYDVPDYA, which is derived from the hemagglutinin surface epitope of influenza virus. It has 9 amino acids and has little impact on the spatial structure of the foreign target protein. It is easy to construct a tag protein fused to the N-terminus or C-terminus. Easy to detect with Anti-HA antibody detection and ELISA. IRES: internal ribosome entry site, the Chinese name is the internal ribosome entry sequence, which can be inserted downstream of the CDS region on the mRNA to mediate another CDS region that follows it, thus enabling the expression of two proteins on one mRNA.
