Neurotransmitter Sensors
rAAV-hSyn-NE1m
The first-generation green fluorescent norepinephrine probe, combining the α2A receptor, with circularly permutated GFP (cpGFP), with kinetics (τon/off ≈ 70-750ms).
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
NE Neurotransmitters NE1m
Neuron-specific Promoter
Store at -80°C
Delivery Information
Usually Ships in 7 Business Days；
Product Details
Functional Gene Details
ChRmine: The excitation wavelength is 635nm, which can provide larger photocurrent and can also generate wave peaks under low-frequency stimulation, so it can be used for manipulations that require lower heat or deeper brain areas. ChRmine can achieve transcranial light activation of specific neural circuits, including midbrain and brainstem structures, to a staggering depth of 7mm, with millisecond precision, and this behavioral modulation does not require surgical intervention. At the same time, the brain areas manipulated by deep transcranial optogenetics were not damaged by tissue heating or other phototoxic effects.
Fluorescent Tag
NE1m
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Fluorescent Protein Details
mCitrine: yellow fluorescent protein, excitation wavelength 516nm, emission wavelength 529nm. Tag protein: HA: The HA tag protein sequence is YPYDVPDYA, which is derived from the hemagglutinin surface epitope of influenza virus. It has 9 amino acids and has little impact on the spatial structure of the foreign target protein. It is easy to construct a tag protein fused to the N-terminus or C-terminus. Easy to detect with Anti-HA antibody detection and ELISA. IRES: internal ribosome entry site, the Chinese name is the internal ribosome entry sequence, which can be inserted downstream of the CDS region on the mRNA to mediate another CDS region that follows it, thus enabling the expression of two proteins on one mRNA.
Expression and Regulation Mode
Others
