Other
rAAV-GfaABC1D-iβARK-P2A-mCherry
iβARK is a 122-residue inhibitory peptide derived from β-adrenergic receptor kinase 1 (βARK1). It selectively blocks Gαq GTP activation, inhibits the Ca2+ signaling mediated by the Gq-GPCR signaling pathway within astrocytes, thereby impacting mouse behavioral activities.
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
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Glial Cell-specific Promoter
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Delivery Information
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Product Details
Fluorescent Tag
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Fluorescent Protein Details
mCitrine: yellow fluorescent protein, excitation wavelength 516nm, emission wavelength 529nm. Tag protein: HA: The HA tag protein sequence is YPYDVPDYA, which is derived from the hemagglutinin surface epitope of influenza virus. It has 9 amino acids and has little impact on the spatial structure of the foreign target protein. It is easy to construct a tag protein fused to the N-terminus or C-terminus. Easy to detect with Anti-HA antibody detection and ELISA. IRES: internal ribosome entry site, the Chinese name is the internal ribosome entry sequence, which can be inserted downstream of the CDS region on the mRNA to mediate another CDS region that follows it, thus enabling the expression of two proteins on one mRNA.
