Optogenetics
rAAV-EF1α-DIO-hsChRmine-mCherry
A recently discovered cation-mediated photosensitive channel protein with high photocurrent, red-shifted spectrum and light sensitivity. (rsChRmine can be activated by near-infrared light, with significantly enhanced red shift; hsChRmine with rapid kinetic enhancement; frChRmine with rapid kinetics and enhanced red shift).
AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro
ChRmine
Broad-spectrum Promoter
Store at -80°C
Delivery Information
Usually Ships in 7 Business Days；
Product Details
Functional Gene Details
ChRmine: The excitation wavelength is 635nm, which can provide larger photocurrent and can also generate wave peaks under low-frequency stimulation, so it can be used for manipulations that require lower heat or deeper brain areas. ChRmine can achieve transcranial light activation of specific neural circuits, including midbrain and brainstem structures, to a staggering depth of 7mm, with millisecond precision, and this behavioral modulation does not require surgical intervention. At the same time, the brain areas manipulated by deep transcranial optogenetics were not damaged by tissue heating or other phototoxic effects.
Fluorescent Tag
mCherry
Fluorescent Protein Details
mCherry: red fluorescent protein, excitation wavelength 587nm, emission wavelength 610nm.
Expression and Regulation Mode
Cre-dependent
