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Apoptosis & Autophagy

rAAV-CAG-DIO-taCasp3-P2A-TEVp

The Casp3 protein is an effector molecule that mediates cell apoptosis. Its precursor is activated into Casp3 during cell apoptosis, which in turn mediates cell apoptosis. taCasp3 is derived from Casp3 with modifications, and it is activated by TEVp (tobacco etch virus protease), inducing cell apoptosis.

Product No.CS-1762
Serotype

AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV8, AAV9, retro, AAV11, AAV13, PHP.eB, BR1, B10, MG1.AAV2, olig001, DJ, php.s, 9/retro

Receptor

taCasp3-P2A-TEVp

Promoter

Broad-spectrum Promoter

Storage

Store at -80°C

Volume
1E+12GC
1E+12GC>1E+14GC
Titer
≥1E+13GC/mL
≥1E+13GC/mL≥5E+12GC/mL
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Delivery Information

Usually Ships in 7 Business Days;

Product Details

Fluorescent Tag

-

Fluorescent Protein Details

mCitrine: yellow fluorescent protein, excitation wavelength 516nm, emission wavelength 529nm. Tag protein: HA: The HA tag protein sequence is YPYDVPDYA, which is derived from the hemagglutinin surface epitope of influenza virus. It has 9 amino acids and has little impact on the spatial structure of the foreign target protein. It is easy to construct a tag protein fused to the N-terminus or C-terminus. Easy to detect with Anti-HA antibody detection and ELISA. IRES: internal ribosome entry site, the Chinese name is the internal ribosome entry sequence, which can be inserted downstream of the CDS region on the mRNA to mediate another CDS region that follows it, thus enabling the expression of two proteins on one mRNA.

Expression and Regulation Mode

Cre-dependent