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Optogenetics

AAV2/9-hSyn-stChRmine-mScarlet-WPRE-pA

Product No.CS-0900
Serotype

AAV2/9, AAV2/2Retro

Receptor

ChRmine

Promoter

hSYN(0.5k) hSyn

Storage

Store at -80°C

Volume
1E+12GC
1E+12GC>1E+14GC
Titer
≥1E+13GC/mL
≥1E+13GC/mL≥5E+12GC/mL
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Delivery Information

Usually Ships in 7 Business Days;

Product Details

Promoter Details

hSyn, human synapsin promoter, mature neuron-specific promoter, 448bp.

Functional Gene Details

ChRmine: The excitation wavelength is 635nm, which can provide larger photocurrent and can also generate wave peaks under low-frequency stimulation, so it can be used for manipulations that require lower heat or deeper brain areas. ChRmine can achieve transcranial light activation of specific neural circuits, including midbrain and brainstem structures, to a staggering depth of 7mm, with millisecond precision, and this behavioral modulation does not require surgical intervention. At the same time, the brain areas manipulated by deep transcranial optogenetics were not damaged by tissue heating or other phototoxic effects.

Fluorescent Tag

red fluorescent red

Fluorescent Protein Details

dsRed, red fluorescent protein, excitation wavelength 557nm, emission wavelength 579nm.

Virus Type

Adeno-associated virus vector Adeno-associated Virus

Expression and Regulation Mode

specific expression