Inhibitory Optogenetics
AAV2/9-hSyn-Fas DO-eNpHR 3.0-EGFP-WPRE-pA
AAV2/9
NpHR
hSYN(0.5k)
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Delivery Information
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Product Details
Promoter Details
hSyn, human synapsin promoter, mature neuron-specific promoter, 448bp.
The h S yn promoter, also known as the h S yn 1 promoter, is cloned from the promoter region of human synapsin protein 1 (S ynapsin 1). It is about 0.5kb in length and is specifically expressed in neurons.
Functional Gene Details
eNpHR3.0: NpHR is a light-driven chloride ion pump belonging to the Halorhodopsin family. The common version is NpHR3.0, which adds an endoplasmic reticulum anterograde transport signal and a Golgi transport signal to the cell membrane based on NpHR, improving its expression on the cell membrane. It is the most commonly used photoinhibition tool. NpHR is usually driven by yellow light around 570nm and can be used simultaneously with hChR2 (H134R).
Fluorescent Tag
green fluorescent green
Virus Type
Adeno-associated virus vector Adeno-associated Virus
Expression and Regulation Mode
specific expression
