Optogenetics
AAV2/8-hSyn-DIO-eArchT3.0-P2A-EGFP-WPRE-pA
AAV2/2Retro, AAV2/8, AAV2/9
ArchT
hSyn-DIO hSYN(0.5k)
Store at -80°C
Delivery Information
Usually Ships in 7 Business Days；
Product Details
Promoter Details
hSyn, human synapsin promoter, mature neuron-specific promoter, 448bp.
The h S yn promoter, also known as the h S yn 1 promoter, is cloned from the promoter region of human synapsin protein 1 (S ynapsin 1). It is about 0.5kb in length and is specifically expressed in neurons.
Functional Gene Details
ArchT: Light-driven outward hydrogen ion pump, belonging to Archaerhodopsin. Compared with Arch, although the maximum current it can form is similar to Arch, ArchT is more than three times more sensitive to light and performs well under 1–10 mW/mm2 illumination. Therefore, under the same conditions, the area that can be suppressed is about twice that of Arch. Its maximum activation wavelength is around 570nm, and it can also be activated with light around 532nm. In some neurons, concentrated firing of action potentials occurs after continuous light inhibition.
Fluorescent Tag
green fluorescent green
Virus Type
Adeno-associated virus vector Adeno-associated Virus
Expression and Regulation Mode
specific expression
