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Synaptic Inhibition

AAV2/2-CAG-DIO-EGFP-2A-TetTox-pA

Product No.CS-0043
Serotype

AAV2/2, AAV2/PHP.eB, AAV2/2Retro, AAV2/8, AAV2/9

Receptor

TetTox TetTox; Tetanus toxin

Promoter

CAG-DIO CAG

Storage

Store at -80°C

Volume
1E+12GC
1E+12GC>1E+14GC
Titer
≥1E+13GC/mL
≥1E+13GC/mL≥5E+12GC/mL
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Delivery Information

Usually Ships in 7 Business Days;

Product Details

Additional Categories

Other Cell Control, Standard Stock

Promoter Details

CAG, strong promoter, an artificially constructed combined promoter, composed of cytomegalovirus early enhancer and chicken β-actin promoter, 1731bp.

The C AG promoter is a combination of the CMV promoter (C), the chicken β-actin intron (A) and the rabbit β-globin intron region (G). It is a strong constitutive promoter with no cell tissue specificity.

The CAG promoter is a combination of the CMV promoter (C), the chicken β-actin intron (A) and the rabbit β-globin intronic region (G). It is a strong constitutive promoter with no cell tissue specificity; functional gene: TetTox, also known as TeNT, is the light chain of Tetanus toxin. It is a protease that can specifically degrade VAMP2, inhibit the release of synaptic glutamate transmitter vesicles, and interrupt neural electrical signal transmission.

Fluorescent Tag

green fluorescent green

Virus Type

Adeno-associated virus vector Adeno-associated Virus

Expression and Regulation Mode

Cre-On

constitutive expression